He accidentally blew most of his face off, including his nose and jaw, with a gun five years ago.
Nine earlier surgical attempts to rebuild his face had failed.
A handful of partial transplants have been carried out since Isabelle Dinoire had her face repaired by French surgeons in 2005.
But until now, no one has had the skill or courage to replace an entire face.
The 24-hour operation involved 30 surgeons, anaesthetists, nurses and other medical experts at the Vall d’Hebron hospital in Barcelona.
The man, who has not been named, received new facial muscles, skin, nose, lips, jaw, teeth, palate and cheekbones.
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